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ZETIA reduces total-CLDL-CApo Bnon-HDL-Cand TGand increases HDL-C in patients with hyperlipidemiaAdministration of ZETIA with a statin is effective in improving serum total-CLDL-CApo Bnon-HDL-CTGand HDL-C beyond either treatment aloneAdministration of ZETIA with fenofibrate is effective in improving serum total-CLDL-CApo Band non-HDL-C in patients with mixed hyperlipidemia as compared to either treatment aloneThe effects of ezetimibe given either alone or in addition to a statin or fenofibrate on cardiovascular morbidity and mortality have not been established.

For High CholesterolI experienced severe abdominal cramps and pain as well as diarrheaI also experienced weakness and fatigueI could not tolerate the drugso I do not know if it had any effect on my cholesterol

No dosage adjustment is necessary in patients with renal impairmentsee CLINICAL PHARMACOLOGYWhen given with simvastatin in patients with moderate to severe renal impairmentestimated glomerular filtration rate.

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